Due to problems with the international supply of plasma, the availability of Human tetanus immunoglobulin (TIG) for prophylaxis is currently extremely limited and supplies of specific TIG are in short supply. It is not yet clear how long the current situation will last. Human tetanus immunoglobulin is a clear, colourless to pale-yellow sterile preparation of immunoglobulin plasma fraction.It is mainly indicated for the prophylaxis and treatment of tetanus, especially suitable for use in individuals hypersensitive to tetanus antitoxin (TAT).
Human Tetanus Immunoglobulin should be administered via the intramuscular route. If a large volume (> 2mL for children or> 5 mL for adults) is required, it is recommended to administer this in divided doses at different sites. When simultaneous vaccination is necessary, the immunoglobulin and the vaccine should be administered at two different sites.
For prophylaxis, if intramuscular administration is contra-indicated (bleeding disorders), the injection can be administered subcutaneously. However, it should be noted that there are no clinical efficacy data to support administration by the subcutaneous route. For acute therapy, if intramuscular administration is not clinically appropriate, an alternative intravenous product may be used if available.Read More: buy Human Tetanus Immunoglobulin
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