Showing posts with label Cosmetic Material. Show all posts
Showing posts with label Cosmetic Material. Show all posts

Tuesday, May 15, 2012

General Knowledeg of Cinnamic Acid

Cinnamic acid is a white crystalline organic acid, which is slightly soluble in water. Cinnamic acid is freely soluble in benzene, diethyl ether, acetone, and it is insoluble in hexane. Cinnamic acid is also a kind of self-inhibitor produced by fungal spore to prevent germination. It is obtained from oil of cinnamon, or from balsams such as storax. It is also found in shea butter and is the best indication of its environmental history and post-extraction conditions. It can also be made synthetically.

Cinnamic acid is used in flavors, synthetic indigo, Allyl cyclohexylpropionate,and certain pharmaceuticals, though its primary use is in the manufacturing of the methyl, ethyl, and benzyl esters for the perfume industry. Cinnamic acid has a honey-like odor; it and its more volatile ethyl ester (ethyl cinnamate) are flavor components in the essential oil of cinnamon, in which related cinnamaldehyde is the major constituent. Cinnamic acid is also part of the biosynthetic shikimate and phenylpropanoid pathways. Its biosynthesis is performed by action of the enzyme phenylalanine ammonia-lyase (PAL) on phenylalanine.

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Monday, May 14, 2012

Information of P-methoxycinnamic Acid

Item Name: P-methoxycinnamic acid        
Molecular Formula: C10H10O3
CAS No.: 830-09-1
Synonyms:
  • 4-Methoxycinnamic acid,predominantly trans;
  • p-Methoxy Cinnamic Acid(trans);
  • 4-Methoxycinnamic acid;
  • 3-(4-methoxyphenyl)acrylic acid;
  • (2E)-3-(4-methoxyphenyl)prop-2-enoic acid
Normally, the bromination of alkenes only result in the anti addition of molecular bromine. However, bromination of p-methoxycinnamic acid results in both syn and anti addition.

People investigated the chemopreventive effect of p-methoxycinnamicacid (p-MCA), an active phenolic acid of rice bran, turmeric, and Kaemperfia galanga against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Male albino Wistar rats were randomly divided into six groups. Group 1 consisted of control rats that received a modified pellet diet and 0.1% carboxymethyl cellulose. The rats in Group 2 received a modified pellet diet supplemented with p-MCA [80 mg/kg body weight (b.wt.) post-orally (p.o.)] everyday. The rats in Groups 3–6 received 1,2-dimethylhydrazine (DMH) (20 mg/kg b.wt.) via subcutaneous injections once a week for the first 4 weeks; additionally, the rats in Groups 4, 5 and 6 received p-MCA at doses of 20, 40 and 80 mg/kg b.wt./day p.o., respectively, everyday for 16 weeks.

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Linalool in Nature


Linalool is a naturally occurring terpene alcohol chemical found in many flowers and spice plants with many commercial applications, the majority of which are based on its pleasant scent (floral, with a touch of spiciness). It has other names such as β-linalool, linalyl alcohol, linaloyl oxide, p-linalool, allo-ocimenol, and 2,6-dimethyl-2,7-octadien-6-ol.

Linalool has a stereogenic center at C3 and therefore two stereoisomers: licareol is (R)-(–)-linalool with CAS No. 126–90–9 (PubChem 67179) and coriandrol is (S)-(+)-linalool with CAS No. 126–91–0 (PubChem 13562).

Over 200 species of plants produce linalool, mainly from the families Lamiaceae (mints, scented herbs), Lauraceae (laurels, cinnamon, rosewood), and Rutaceae (citrus fruits), but also birch trees and other plants, from tropical to boreal climate zones. It has also been found in some fungi.

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Friday, May 11, 2012

Cinnamaldehyde's Structure



Cinnamaldehyde is the organic compound that gives cinnamon its flavor and odor. This pale yellow viscous liquid occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum. The essential oil of cinnamon bark is about 90% cinnamaldehyde.

Cinnamaldehyde was isolated from cinnamon essential oil in 1834 by Dumas and Péligot[citation needed] and synthesized in the laboratory by Chiozza in 1854.

The natural product is trans-cinnamaldehyde. The molecule consists of a phenyl group attached to an unsaturated aldehyde. As such, the molecule can be viewed as a derivative of acrolein. Its color is due to the π → π* transition: increased conjugation in comparison with acrolein shifts this band towards the visible.

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General Introduction of Arbutin


Item Name: Arbutin 
Molecular Formula: C12H16O7
CAS No.: 497-76-7

Arbutin is both an ether and a glycoside; a glycosylated hydroquinone extracted from bearberry plant in the genus Arctostaphylos. It inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Arbutin is found in wheat, and is concentrated in pear skins. It is also found in Bergenia crassifolia.
Bearberry extract is used in skin lightening treatments designed for long term and regular use. An active agent in brands of skin lightening preparations, it is more expensive than traditional skin lightening ingredients like hydroquinone, which is now banned in many countries.

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Thursday, May 10, 2012

Findings of Ferulic Acid Ethyl Ester

Molecular Formula: C12H14O4
CAS No.: 4046-02-0

Ferulic acid is a hydroxycinnamic acid, a type of organic compound. It is an abundant phenolic phytochemical found in plant cell wall components such as arabinoxylans as covalent side chains. Topical sunscreens have been used for many years on exposed areas to protect the skin from the damaging effects of ultraviolets. If the sunscreens were essential, it is suggested that they have adverse effects. We chose to study ferulic acid ethyl ester (FAEE) as agent which could potentially be used in sunscreen products. FAEE was incorporated at various concentrations into O/W emulsions. Total of 30 mg of product exactly weighed were spread on poly(methylmethacrylate) plates over the whole surface (25 cm(2)). So, sun protection factor (SPF) and PF-UVA of the creams were measured in vitro. Transmission measurements between 290 and 400 nm were carried out using a spectrophotometer equipped with an integrating sphere. Incorporated in O/W creams, at a concentration of 10%, FAEE give a SPF similar to that of benzymidazilate, a filter permitted in EU.

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Applications of Alfa-Lipoic Acid



Lipoic acid (LA), also known as α-lipoic acid and alpha lipoic acid (ALA) is an organosulfur compound derived from octanoic acid. LA contains two vicinal sulfur atoms (at C6 and C8) attached by a disulfide bond and is thus considered to be oxidized (although either sulfur atom can exist in higher oxidation states). The carbon atom at C6 is chiral and the molecule exists as two enantiomers R-(+)-lipoic acid (RLA) and S-(-)-lipoic acid (SLA) and as a racemic mixture R/S-lipoic acid (R/S-LA). Only the R-(+)-enantiomer exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Endogenously synthesized RLA is essential for life and aerobic metabolism. Both RLA and R/S-LA are available as over-the-counter nutritional supplements and have been used nutritionally and clinically since the 1950s for various diseases and conditions. LA appears physically as a yellow solid and structurally contains a terminal carboxylic acid and a terminal dithiolane ring.

Applications of Alfa-Lipoic Acid:
  • Use as a dietary supplement
  • Antioxidant
  • Disease Treatment
  • Use as a chelator
  • R-enantiomer and S-enantiomer
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Tuesday, May 8, 2012

Some Knowledge About α-Ionone

Item Name:           α-iononeMolecular Formula:     C13H20O
CAS No.:      127-41-3
Description of  α-Ionone:
Appearence:Colorless to pale yellow liquid 
Odor Description ; Warm woody resin-like sweet floral

The ionones are a series of closely related chemical substances that are part of a group of compounds known as rose ketones, which also includes damascones and damascenones. Ionones are aroma compounds found in a variety of essential oils, including rose oil. beta-Ionone is a significant contributor to the aroma of roses, despite its relatively low concentration, and is an important fragrance chemical used in perfumery. The ionones are derived from the degradation of carotenoids.

The combination of alpha-Ionone and beta-Ionone is characteristic of the scent of violets and used with other components in perfumery and flavouring to recreate their scent.

The carotenes alpha-carotene, beta-carotene, gamma-carotene, and the xanthophyll beta-cryptoxanthin, all contain beta-ionone, and thus have vitamin A activity because they can be converted by plant-eating animals to retinol and retinal. Carotenoids that do not contain the beta-ionone moiety cannot be converted to retinol, and thus have no vitamin A activity.

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The Production of p-Anisaldehyde


4-Anisaldehyde (also known as: p-anisaldehyde, anisic aldehyde) is an organic compound that is commonly encountered in the fragrances, both synthetic and natural. The compound consists of a benzene ring substituted with an aldehyde and a methoxy group. It is a clear liquid with a strong aroma. Two related isomers ortho-anisaldehyde and meta-anisaldehyde are also known but less commonly encountered.

Anisaldehyde is prepared commercially by oxidation of methoxytoluene (p-cresyl methyl ether) using manganese dioxide. It can also be produced by oxidation of anethole, a related fragrance that is found in some alcoholic beverages.

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Monday, May 7, 2012

Brief Information of Potassium Stearate

Potassium stearate is a kind of fine white, fluffy powder with greasy touch sense and fatt odor. It is soluble in hot water or alcohol, and its solvent is alkaline because of hydrolysis. In addition, potassium stearate is anion type surface active agent,which widly applied in acrylate rubber soap/sulfur and vulcanized system.

Item Name:        potassium stearate 
Molecular Formula:    C18H35KO2
CAS No.:       593-29-3
Molecular Weight: 322.57
Purity: ≥ 98.0%
Applications of Potassium Stearate:
1.Applied in food,medicine,cosmetic plastic,
2.As emulsifier,dispersing agent,lubircant,surface processin

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Sunday, May 6, 2012

Lanoline's Composition

Like many natural products, lanolin has a complex and variable composition. For example, a typical high purity grade of lanolin is composed predominantly of long chain waxy esters (ca. 97% by weight) the remainder being lanolin alcohols, lanolin acids and lanolin hydrocarbons.

It has been estimated that there may be between 8,000 and 20,000 different types of lanolin ester present in lanolin resulting from combinations between the ca. 200 different lanolin acids and the ca. 100 different lanolin alcohols that have so far been identified.

Lanolin's complex composition of long chain esters, hydroxy esters, diesters, lanolin alcohols, lanolin acids means that in addition to it being a valuable product in its own right, it is also the starting point for the production of a whole spectrum of lanolin derivatives which possess wide-ranging chemical and physical properties. The main derivatisation routes include hydrolysis, fractional solvent crystallisation, esterification, hydrogenation, alkoxylation and quaternisation Lanolin derivatives obtained from these processes are used widely in both high-value cosmetic and skin treatment products.

Hydrolysis of lanolin yields lanolin alcohols and lanolin acids. Lanolin alcohols are a rich source of cholesterol (an important skin lipid) and are powerful water-in-oil emulsifiers; they have been used extensively in skin care products for over 100 years. Interestingly, approximately 40% of the acids derived from lanolin are alpha hydroxy acids. The use of alpha hydroxy acids (AHA’s) in skin care products has attracted a great deal of attention in recent years.
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Thursday, May 3, 2012

A Description of N-Heptanol


Item Name:         n-heptanol
Molecular Formula:  C7H16O
CAS No.:                111-70-6
Description of N-Heptanol:
Appearance and properties: colorless transparent liquid, aromatic odor.
Melting point (℃): -34.6
Relative density (water = 1): 0.82
Boiling point (℃): 175.8
Molecular formula: C7H16O
Molecular Weight: 116.20
Saturated vapor pressure (kPa): 0.13 (42.4 ° C)
Heat of combustion (kJ / mol): 4618.5
Flash point (℃): 77 (O.C)
Solubility: slightly soluble in water, soluble in alcohol, ether.
N-heptanol is a kind of colorless liquid with a fragrant odor. It is used as an intermediate, solvent and in cosmetics. 1-Heptanol is an alcohol with a seven carbon chain and the structural formula of CH3(CH2)6OH. It is a clear colorless liquid that is very slightly soluble in water, but miscible with ether and ethanol.
The natural materials of n-heptanol can be found in the essential oil of clove, hyacinth, violet leaves. Slightly soluble in water, miscible with ethanol, ether, etc.. Oxidizable and esterification. Exist in the fusel oil. By are heptaldehyde Restore or bromide, pentyl magnesium and ethylene oxide synthesis. N-heptanol is alway used as reagents for Organic Synthesis.


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The Occurrence of Titanium Dioxide


Titanium dioxide occurs in nature as well-known minerals rutile, anatase and brookite, and additionally as two high pressure forms, a monoclinic baddeleyite-like form and an orthorhombic α-PbO2-like form, both found recently at the Ries crater in Bavaria. The most common form is rutile, which is also the equilibrium phase at all temperatures. The metastable anatase and brookite phases both convert to rutile upon heating. Rutile, anatase and brookite all contain six coordinated titanium.

Titanium dioxide has eight modifications – in addition to rutile, anatase and brookite there are three metastable forms produced synthetically (monoclinic, tetragonal and orthorombic), and five high pressure forms (α-PbO2-like, baddeleyite-like, cotunnite-like, orthorhombic OI, and cubic phases).

The cotunnite-type phase was claimed by L. Dubrovinsky and co-authors to be the hardest known oxide with the Vickers hardness of 38 GPa and the bulk modulus of 431 GPa (i.e. close to diamond's value of 446 GPa) at atmospheric pressure. However, later studies came to different conclusions with much lower values for both the hardness (7–20 GPa, which makes it softer than common oxides like corundum Al2O3 and rutile TiO2) and bulk modulus (~300 GPa).

The naturally occurring oxides can be mined and serve as a source for commercial titanium. The metal can also be mined from other minerals such as ilmenite or leucoxene ores, or one of the purest forms, rutile beach sand. Star sapphires and rubies get their asterism from rutile impurities present in them.

Titanium dioxide (B) is found as a mineral in magmatic rocks and hydrothermal veins, as well as weathering rims on perovskite. TiO2 also forms lamellae in other minerals. Spectral lines from titanium oxide are prominent in class M stars, which are cool enough to allow molecules of this chemical to form.

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Wednesday, May 2, 2012

Description of Matrixyl Acetate

Item Name:             Matrixyl Acetate
Molecular Formula:  C39H75N7O10
Description of Matrixyl Acetate:
Molecular Weight: 802.05
Storage: 2 to 8 º C
Sequence: PAL-Lys-Thr-Thr-Lys-Ser-OH
Appearance: White powder
Water Content(Karl Fischer): d5.0%
Acetate Content(by HPLC): d15.0%
Amino Acid Composition: ± 10% of theoretical
Purity (by HPLC): e95.0%
Single Impurity(by HPLC): d2.0%
Peptide Content(by %N ): e80%
Assay(By Anhydrous, Acetic Acid-free ): 95.0% to 105.0%
Bacterial Endotoxins: d10EU/mg
Usage: Anti-Wrinkle
Matrixyl is a lipopeptide. Lipopeptides are substances that are a combination of amino and fatty acids. Matrixyl is used to fight aging, give skin a more youthful appearance and enhance the overall appearance of the skin.
An acetate is a derivative of acetic acid. This term includes salts and esters, as well as the anion found in solution. Most of the approximately 5 billion kilograms of acetic acid produced annually in industry are used in the production of acetates, which usually take the form of polymers. In nature, acetate is the most common building block for biosynthesis. For example, the fatty acids are produced by connecting C2 units derived from acetate.


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Bromelain’s Extract Components

Bromelain is extracted from the stems of pineapples. It has a history of folk and modern medicinal use. As a supplement it is thought to have anti-inflammatory effects. As a culinary ingredient it is primarily used as a tenderizer. Bromelain also contains chemicals that might interfere with the growth of tumor cells and slow blood clotting, according to laboratory research.
The term "bromelain" can refer to either of two protease enzymes extracted from the plant family Bromeliaceae, or it can refer to a combination of those enzymes along with other compounds produced in an extract.
Bromelain extract is a mixture of protein-digesting enzymes—called proteolytic enzymes or proteases and several other substances in smaller quantities. The proteolytic enzymes are referred to as sulfhydryl proteases, since a free sulfhydryl group of a cysteine side-chain is required for function. The two main enzymes are:
Stem bromelain - EC 3.4.22.32
Fruit bromelain - EC 3.4.22.33
The other substances typically include peroxidase, acid phosphatase, protease inhibitors, and calcium.


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Tuesday, May 1, 2012

A Little Knowledge Related to 2-Bromo-5-Fuoropyridine

Item Name:         2-bromo-5-fluoropyridine
Molecular Formula:         C5H3BrFN
CAS No.:       41404-58-4
Categories:
Fluorin-contained pyridine series; 
blocks; Bromides;
Fluoro Compounds;
Pyridines; Pyridine;
Pyridines, Pyrimidines, Purines and Pteredines;
Pyridine series
Properties of 2-bromo-5-fluoropyridine
Mp 30-31 °C(lit.)
bp 80-83 °C44 mm Hg(lit.)
Refractive index: 1.5396
Fp 167 °F
Storage temp.  Store Cold
BRN 1561456
Fluorine is the chemical element with atomic number 9, represented by the symbol F. It is the lightest element of the halogen column of the periodic table and has a single stable isotope, fluorine-19. At standard pressure and temperature, fluorine is a pale yellow gas composed of diatomic molecules, F2. In stars, fluorine is rare compared to other light elements. In Earth's crust, fluorine is more common, being the 13th most abundant element.

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Thursday, April 26, 2012

Main Applications of Butyl Propionate


Butyl propionate, which is also called n - propionate, (C7H12O2). Its relative molecular weight is 128.17, and its structure is H2C = CHCOOCH2CH2CH2CH3. It is acryloyl compound.
Butyl propionate is mainly used as intermediates in organic synthesis, adhesives, emulsifiers, and coatings. Acid and its esters are widely used in industry. During use, it often aggregates into the acrylic polymer or copolymer. Butyl acrylate (methyl, ethyl, 2 - ethylhexyl ester) is a soft monomer, with a variety of hard monomers such as methyl methacrylate, styrene, acrylonitrile, vinyl acetate, and functional monomers such as (meth) acrylic acid hydroxyethyl methacrylate, hydroxypropyl acrylate, glycidyl (meth) acrylamide and its derivatives, copolymerization, crosslinking, grafting, etc., made ​​200-700 a variety of acrylic resin products (emulsion, solvent-and water-soluble type). Butyl propionate is widely used as coatings, adhesives, acrylic fiber modification, plastic modification, fiber and fabric processing, paper processing agents, leather processing and acrylic rubber and many other aspects.

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