Properties of Isonipectoamide

Item name: Isonipectoamide
CAS: 39546-32-2
Molecular Formula: C6H12N2O
Formula Weight: 128.17
Properties of Isonipectoamide:
Density: 1.06 g/cm3
Melting Point: 145-148 °C
Boiling Point: 311.7 ºC at 760 mmHg
Flash Point: 142.3 ºC
Appearance: White to light yellow crystalline powder.
Use: Used as medicine intermediate.

In (IV), head-to-tail primary cation-anion associations are extended longitudinally into chains through the water-bridged cation associations, and laterally by piperidinium-carboxylate N-H···O and water-carboxylate O-H···O hydrogen bonds. The structures reported here further demonstrate the utility of the isonipecotamide cation as a synthon for the generation of stable hydrogen-bonded structures. An additional example of cation-anion association with this cation is also shown in the asymmetric three-centre piperidinium-carboxylate N-H···O,O' interaction in the first-reported structure of a 2:1 isonipecotamide-carboxylate salt.

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Specifications of Tetrahydrothiopyran-4-One

Product name: Tetrahydrothiopyran-4-one

CAS: 1072-72-6
Molecular Formula: C5H8OS
Formula Weight: 116.18
Specifications of Tetrahydrothiopyran-4-One:
Density: 1.134 g/cm3
Melting Point :60-64 °C(lit.)
Boiling Point: 218.7 °C at 760 mmHg
Flash Point: 105.5 °C
Appearance: White to pale yellow crystalline solid
Use: Used as medicine intermediate

As shown, with 5 mol% of 1,1-dioxotetrahydrothiopyran-4-one as catalyst,10 epoxidation of various olefins (2-mmol scale) in a homogeneous acetonitrile-water solvent system with 1.5 equiv of Oxone ® at room temperature can be achieved in a short period of time with excellent yields of epoxides (80-97%) isolated by flash column chromatography.2 As the pH of the reaction is maintained at 7-7.5 by sodium bicarbonate , acid- or base-labile epoxides (entries 12-14) can be easily isolated without decomposition. More importantly, the in situ epoxidation of olefins can be performed on a large scale directly with 5 mol% of tetrahydrothiopyran-4-one , which is oxidized immediately by Oxone ® to 1,1-dioxotetrahydrothiopyran-4-one during the epoxidation reactions. For example, with 5 mol% of tetrahydrothiopyran-4-one , substrates 3, 5 (20 mmol each) and 11 (100 mmol) were epoxidized with excellent isolated yields of epoxides (91-96%).
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Specifications of Pyrimidine-4-Carboxylic Acid

Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring.[2] It is isomeric with two other forms of diazine: Pyridazine, with the nitrogen atoms in positions 1 and 2; and Pyrazine, with the nitrogen atoms in positions 1 and 4.

Item name: Pyrimidine-4-carboxylic acid

CAS: 31462-59-6
Molecular Formula: C5H4N2O2
Formula Weight: 124.1
Specifications of Pyrimidine-4-Carboxylic Acid:
Density: 1.403 g/cm3
Melting Point: 229.8-231.9 °C
Boiling Point: 318.7 °C at 760 mmHg
Flash Point: 146.5 °C
Appearance: white solid.
Storage: In ventilate and dry places.

Carboxylic acids are organic acids characterized by the presence of at least one carboxyl group. The general formula of a carboxylic acid is R-COOH, where R is some monovalent functional group. A carboxyl group (or carboxy) is a functional group consisting of a carbonyl (RR'C=O) and a hydroxyl (R-O-H), which has the formula -C(=O)OH, usually written as -COOH or -CO2H.
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Description of 2-Chloro Phenyl Glycine

Item name: 2-Chloro Phenyl Glycine

CAS: 88744-36-9
Molecular Formula: C8H8ClNO2
Formula Weight: 185.61
Description of 2-Chloro Phenyl Glycine:
Use: Used as medicine intermediate.
Storage: Store under inert gas
Synonyms: Glycine,2-(o-chlorophenyl)- (7CI); (R,S)-a-Amino-a-(2-chlorophenyl)aceticacid; 2-(2-Chlorophenyl)glycine

Glycine (abbreviated as Gly or G) is an organic compound with the formula NH2CH2COOH. Having a hydrogen substituent as its side-chain, glycine is the smallest of the 20 amino acids commonly found in proteins. Its codons are GGU, GGC, GGA, GGG cf. the genetic code.

Glycine is a colourless, sweet-tasting crystalline solid. It is unique among the proteinogenic amino acids in that it is not chiral. It can fit into hydrophilic or hydrophobic environments, due to its two hydrogen atom side chain.

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The Preparation of Tetrakis(Triphenylphosphine)Palladium(0)

Tetrakis(triphenylphosphine)palladium(0) is the chemical compound Pd[P(C6H5)3]4, often abbreviated Pd(PPh3)4, or even PdP4. It is a bright yellow crystalline solid that becomes brown upon decomposition in air.

Tetrakis(triphenylphosphine)palladium(0) was first prepared by Lamberto Malatesta and his group in Milan in the 1960s by reduction of sodium chloropalladate with hydrazine in the presence of the phosphine. It is commercially available, but can be prepared in two steps from Pd(II) precursors:

 PdCl2 + 2 PPh3 → cis-PdCl2(PPh3)2
cis-PdCl2(PPh3)2 + 2 PPh3 + 2.5 N2H4 → Pd(PPh3)4 + 0.5 N2 + 2 N2H5+Cl-

Both steps may be carried out in a one-pot reaction, without isolating and purifying the cis-PdCl2(PPh3)2 intermediate. Reductants other than hydrazine can be employed. The compound is sensitive to air, but can be purified by washing with methanol to give the desired yellow powder. It is usually stored cold under argon.
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Properties of Vinylmagnesium Bromide

Item name:Vinylmagnesium bromide
CAS:1826-67-1
Molecular Formula:C2H3BrMg
Formula Weight:131.25
Properties of Vinylmagnesium Bromide:
Density:0.981 g/mL at 25 °C
Flash Point:-17 oC
Solubility:vigorous reaction.
Storage:Refrigerator.
Soubility:vigorous reaction
Use:Used as medicine intermediate.

A bromide is a chemical compound containing a bromide ion, that is a bromine atom with an effective charge of −1. The class name can include ionic compounds such as caesium bromide or covalent compounds such as sulfur dibromide.

Bromide is present in typical seawater (35 PSU) with a concentration of around 65 mg/L, which is around 0.2% of all dissolved salts. Seafoods and deep sea plants generally have high levels of bromide, while foods derived from land have variable amounts.

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Nafarelin Acetate's Dosage in Children

Nafarelin acetate is a gonadotropin-releasing hormone (GnRH) agonist proven as effective as danazol in treating endometriosis. Its proposed mechanism of action is the desensitization of pituitary GnRH receptors leading to a decrease in gonadotropin release, and ovarian hormone serum concentrations similar to those achieved in postmenopausal women.

Item name: Nafarelin Acetate
CAS: 86220-42-0
Molecular Formula: C68H89N17O16
Formula Weight: 1400.54

In children, nafarelin acetate was rapidly absorbed into the systemic circulation after intranasal administration. Maximum serum concentrations (measured by RIA) were achieved between 10 and 45 minutes. Following a single dose of 400 µg base, the observed peak concentration was 2.2 ng/mL, whereas following a single dose of 600 µg base, the observed peak concentration was 6.6 ng/mL. The average serum half-life of nafarelin following intranasal administration of a 400 µg dose was approximately 2.5 hours. It is not known and cannot be predicted what the pharmacokinetics of nafarelin will be in children given a dose above 600 µg.

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Description of 3,5-Di-O-(p-toluyl)-2-Deoxy-D-Ribofuranosyl Chloride

Item name: 3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride
CAS: 3601-89-6
Molecular Formula: C21H21ClO5
Formula Weight: 388.85
Description of 3,5-Di-O-(p-toluyl)-2-Deoxy-D-Ribofuranosyl Chloride:
Melting Point:1 09°C dec.
Use: Used as medicine intermediate.
Storage: Store the product under dry environment with low temperature; avoid light.
Item Categories: 13C & 2H Sugars;Carbohydrates & Derivatives

The chloride ion is formed when the element chlorine, a halogen, gains an electron to form an anion (negatively-charged ion) Cl−. The salts of hydrochloric acid contain chloride ions and can also be called chlorides. The chloride ion, and its salts such as sodium chloride, are very soluble in water. It is an essential electrolyte located in all body fluids responsible for maintaining acid/base balance, transmitting nerve impulses and regulating fluid in and out of cells.

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Details of 6-Methoxy-3,4-Dihydronaphthalen-2-One

Item name:6-methoxy-3,4-dihydronaphthalen-2-one
CAS:2472-22-2
Molecular Formula:C11H12O2
Formula Weight:                     176.21
Details of 6-Methoxy-3,4-Dihydronaphthalen-2-One:
Density:1.124 g/cm3
Melting Point:28-35 ºC
Boiling Point:114-116 ºC (0.2 mmHg),319.4 °C at 760 mmHg
Flash Point:>110 ºC
Appearance:White Crystal.
Use:Used as medicine intermediate.
Storage:0-6°C

Methoxy is used in organic nomenclature usually to describe an ether. It is also an electron-donating group and can cause an organic compound to become less acidic.

The simplest case is another methyl group giving dimethyl ether; other methoxy ethers are methoxyethane and methoxypropane. In the field of natural compounds, examples bearing methoxy groups are O-methylated flavonoids. It is also found in Mescaline and its analogues, 2C-B, 2C-E and 2C-P for instance.

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Some Information of Piperonylamine

Item name:Piperonylamine
 CAS:             2620-50-0
 Molecular Formula:C8H9NO2
 Formula Weight:             151.16
 Specifications of Piperonylamine:
 Boiling point:138-139 °C13 mm Hg(lit.)
 Flash Point:>230 °F
 Density:1.214 g/mL at 25 °C(lit.)
 Solubility:Stable under ordinary conditions.0.9 g/100 mL
 Apperance:clear to yellow liquid.
 Use:used in making veterinary medicines, insecticides and pediculicides.

The present invention provides N-propargyl-piperonylamine of its addition salts. By addition salts are meant the addition salts with acids obtained by reaction of the free base with an inorganic or organic acid. Suitable acids include hydrochloric acid, hydrobromic acid, sulphuric acid, phosphoric acid, nitric acid, formic acid, acetic acid, oxalic acid, fumaric acid, maleic acid, malic acid, citric acid, tartaric acid, ascorbic acid, glutamic acid, aspartic acid, methanesulphonic acid, p-toluenesulphonic acid and succinic acid.

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Specifications of 1-Bromo-2,6-Dichlorobenzene

1-Bromo-2,6-dichlorobenzene is a kind of white crystalline powder and chunks. It is usually used as medicine intermediate.

Item name: 1-Bromo-2,6-dichlorobenzene

CAS: 19393-92-1
Molecular Formula: C6H3BrCl2
Formula Weight: 225.9
Specifications of 1-Bromo-2,6-dichlorobenzene:
Density: 1.744 g/cm3
Melting Point: 61-64 °C(lit.)
Boiling Point: 242 °C765 mm Hg(lit.)
Flash Point: >100°C

1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C6H4Cl2. This colourless liquid is poorly soluble in water but miscible with most organic solvents. It is a derivative of benzene, consisting of two adjacent chlorine centers.

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An Introduction of Phytine

Item name: Phytine
CAS: 7776-28-5
Molecular Formula: C6H6Ca6O24P6
Formula Weight: 888.41
Description:
Phytine is light yellow slurry liquid, soluble in water, ethanol, acetone, insoluble in anhydrous ether, benzene, hexane, chloroform.
Phytine is used as chelating, antioxidant,antistaling agent, and water softener etc, and it is widely used in food, medicine, painting and chemical industry for daily use.

Phytin is indicated as a stimulating agent; in nervous system diseases (neurosis, impotence), memory weakening, insomnia; loss of appetite; secondary anemia (together with iron containing agents); bone diseases (rachitis, osteomalacia, fractures) in children with diatheses; in the convalescent period after severe diseases.

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Properties of 2,5-Dichloropyrimidine

Item name: 2,5-Dichloropyrimidine

CAS: 22536-67-0
Molecular Formula: C4H2Cl2N2
Formula Weight: 148.98
Properties of 2,5-Dichloropyrimidine:
Melting point: 57.0-57.5°C
Boiling point: 190°C
Flash Point: 140°C
Density: 1.493g/cm3

2,5-Dichloropyrimidine is a type of off white crystall. It is most commonly used as Pharmaceutical intermediates. [2-14 C]2,5-dichloropyrimidine is a useful reagent for labeling biologically active compounds for use in hepatocyte transport studies, protein covalent binding, and metabolic profiling.

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Description of 4-Iodopyrazole

4-Iodopyrazole is a type of off-white crystalline powder. It is always used as medicine intermediate. Because of its own properties, it should be stored in ventilate, cool and dry places. The metabolism of MAM by rat liver microsomes is sensitive to inhibition by carbon monoxide as well as to inhibition by 3-methylpyrazole (3-MeP) and 4-iodopyrazole (4-IP), with 4-IP being more potent in this respect than 3-MeP.

Item name: 4-Iodopyrazole
CAS: 3469-69-0
Molecular Formula: C3H3IN2
Formula Weight: 193.97
Description of 4-Iodopyrazole:
Density: 2.335 g/cm3
Melting Point: 108-110ºC
Boiling Point: 291.9ºCat 760 mmHg
Flash Point: 130.3ºC
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Information of 2,3,5,6-Tetramethyl-1,4-Phenylenediamine

p-Phenylenediamine (PPD)(1,4-phenylenediamine) is an organic compound with the formula C6H4(NH2)2. This derivative of aniline is a colorless solid, but typically samples can contain yellowish impurities arising from oxidation. It is mainly used as a component of engineering polymers and composites. It is also an ingredient in hair dyes.

Item name:2,3,5,6-Tetramethyl-1,4-phenylenediamine

CAS: 3102-87-2
Molecular Formula: C10H16N2
Formula Weight: 164.25
Information of 2,3,5,6-Tetramethyl-1,4-Phenylenediamine:
Density: 1.032 g/cm3
Melting Point: 150-155 °C(lit.)
Boiling Point: 310.6 °C at 760 mmHg
Flash Point: 167.8 °C
Appearance: light yellow powder.
Use: Used as medicine intermediate.
Storage: under cool dry place or refrigerator ventilation optimal cryopreservation.

PPD is a precursor to aramid plastics and fibers such as Kevlar. These applications exploit PPD's difunctionality, i.e. the presence of two amines which allow the molecules to be strung together. This polymer arises from the reaction of PPD and terephthaloyl chloride. The reaction of PPD with phosgene gives the diisocyanate, a precursor to urethane polymers.

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Introduction of (+)-Usniacin

Item name: (+)-Usniacin

CAS: 125-46-2

Molecular formula: C18H16O7

Molecular Weight: 344.32

Alias: usnic acid; (+)-Usnic acid; (+)-Usnein; (+)-Usniacin; D-2,6-Diacetyl-7,9-dihydroxy-8, 9b-dimethyl-1, 3 (2H , 9bH) - Dibenzofurandione;

Appearance: yellow crystalline powder.

Melting point: 192-204 ° C

Optical rotation: [α] D20 +495 ° ~ 497 ° (C = 1, in of CHCl3)

Stability: Normally stable.

(+)-Usniacin is a naturally occurring dibenzofuran derivative found in several lichen species.Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases the compound was found in kombucha tea and non-lichenized ascomycetes.

At normal conditions, usnic acid is a bitter, yellow, solid substance. It is known to occur in nature in both the d- and l-forms as well as a racemic mixture.

(+)-Usniacin is from natural Usnea. It is used to stop bleeding, anti-bacterial, anti-inflammatory, wound healing, in addition to the plaque, enhance immunity, oral ulcer disease, and vaginitis have a good effect. Often as toothpaste and cosmetics additive.Usnic acid is extracted from Usnea. It is used as an antibacteria agnet in cosmetics and ointments to prevent skin infection. It is also used in formulating deodorant, mouth-care products.

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Introduction of 3,5-Dimethyl-4-Hydroxy Acetophenone

Item name: 3,5-Dimethyl-4-hydroxy acetophenone

CAS: 5325-04-2
Molecular Formula: C10H12O2
Formula Weight: 164.2
Introduction of 3,5-Dimethyl-4-Hydroxy Acetophenone:
Melting point: 151-155 °C(lit.)
Use: Used as medicine intermediate.
Storage: Store the product under dry environment with low temperature.
Product Categories: Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones

Acetophenone is the organic compound with the formula C6H5C(O)CH3. It is the simplest aromatic ketone. This colourless, viscous liquid is a precursor to useful resins and fragrances.

Acetophenone can be obtained by a variety of methods. In industry, acetophenone is recovered as a by-product of the oxidation of ethylbenzene, which mainly gives ethylbenzene hydroperoxide for use in the production of propylene oxide.

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Description of 4-Aminopyridine-2-Carboxylic Acid

Item name:4-Aminopyridine-2-carboxylic acid

CAS:100047-36-7
Molecular Formula:C6H6N2O2
Formula Weight:138.12
Description of 4-Aminopyridine-2-Carboxylic Acid:
Density:1.417g/cm3
Boiling Point:446.3°Cat760mmHg
Flash Point:223.7°C
Use:Used as medicine intermediate.
Storage:In ventilate and dry places.

4-Aminopyridine (4-AP) is prepared by the decarbonylation of pyridine-4-carboxamide using sodium hypochlorite via the Hofmann rearrangement. The pyridine carboxamide is generated from the corresponding nitrile, which in turn is obtained from ammoxidation of 4-methylpyridine.

Carboxylic acids are organic acids characterized by the presence of at least one carboxyl group. The general formula of a carboxylic acid is R-COOH, where R is some monovalent functional group. A carboxyl group (or carboxy) is a functional group consisting of a carbonyl (RR'C=O) and a hydroxyl (R-O-H), which has the formula -C(=O)OH, usually written as -COOH or -CO2H.

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Brief Description of 4-(1H-1,2,4-Triazol-1-yl)Aniline

Item name: 4-(1H-1,2,4-Triazol-1-yl)aniline

CAS: 6523-49-5

Molecular Formula: C8H8N4

Formula Weight: 160.18

Description of 4-(1H-1,2,4-Triazol-1-yl)Aniline:

Melting Point: 142 °C

Use: Intermediate in organic syntheses.

Storage: Stored in normal temperature.

Safety: Poison by intravenous route. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of a phenyl group attached to an amino group, aniline is the prototypical aromatic amine. Being a precursor to many industrial chemicals, its main use is in the manufacture of precursors to polyurethane. Like most volatile amines, it possesses the somewhat unpleasant odour of rotten fish. It ignites readily, burning with a smoky flame characteristic of aromatic compounds. Aniline is colorless, but it slowly oxidizes and resinifies in air, giving a red-brown tint to aged samples.

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Knowledge of 4-Imidazole Acrylic Acid Dihydrate

4-Imidazole acrylic acid dihydrate,also known as Urocanic acid,is an intermediate in the catabolism of L-histidine. Urocanic acid was detected in animal sweat and skin where, among other possible functions, it acts as an endogenous sunscreen or photoprotectant against UVB-induced DNA damage. Urocanic acid is found predominantly in the stratum corneum of the skin and it is likely that most of it is derived from filaggrin catabolism (a histidine-rich protein). When exposed to UVB irradiation, trans-urocanic acid is converted in vitro and in vivo to the cis isomer. The cis form is known to activate suppressor T cells.

Item name:4-Imidazole acrylic acid dihydrate
CAS:104-98-3
Molecular Formula:C6H10N2O4
Formula Weight:174.15

Acrylic acid (IUPAC: prop-2-enoic acid) is an organic compound with the formula CH2=CHCO2H. It is the simplest unsaturated carboxylic acid, consisting of a vinyl group connected directly to a carboxylic acid terminus. This colorless liquid has a characteristic acrid or tart smell. It is miscible with water, alcohols, ethers, and chloroform. More than one billion kilograms are produced annually.
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