How to Get Anti-CXC-R3/CD183?

The main function of the antibody and antigen (including foreign and self) are combined to effectively clear the microorganisms invade the body, parasites and other foreign matter, and they release toxins or remove some of the autoantigen, so that the body to maintainnormal balance, but sometimes cause pathological damage to the body, such as antinuclear antibodies, anti-double stranded DNA antibodies, the generation of anti-thyroglobulin antibodies and other autoantibodies to the human body can cause harm.

Chemokine receptor CXCR3 is a Gαi protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183.
CXCR3 is able to regulate leukocyte trafficking. Binding of chemokines to CXCR3 induces various cellular responses, most notably integrin activation, cytoskeletal changes and chemotactic migration. CXCR3-ligand interaction attracts Th1 cells and promotes Th1 cell maturation. Anti-CXC-R3/CD183 should be stored at -20 ° C. It should be stored at low temperatures, if it prolong exposure to the air, the content will be reduced.

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