Tuesday, March 27, 2012

What Is Trypsin-Chymotrypsin 1-1?

Trypsin-Chymotrypsin 1-1 Trypsin-Chymotrypsin 1-1is a beige to tan, amorphous powder that is derived from bovine pancrease. All glands are of North American origin. Both Trypsin, 3.4.21.4, and Chymotrypsin 3.4.21.1, are classed as serine Proteases. Chymotrypsin preferentially cleaves Tyr, Tryp, Phe, Leu. The pH optimum is 8 - 9 with a temperature optimum of 35 C. Typsin preferentially cleaves Arg and Lys. It's pH optimum is 8 - 9 with a temperature optimum of 45 C.
The activity of hydrolyze ester bond similar to that of Trypsin. It is stable when dry and easy to be inactivated in solutions. The optimum pH of Trypsin-Chymotrypsin 1-1 is 7.0-8.0. In addition, it shoule be stored in low humidity at less than 20 C.

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