Tuesday, March 20, 2012

The Use of Anti-EGFR-ⅤⅢ

Anti-EGFR-ⅤⅢ  
Anti-EGFR-ⅤⅢ is also called chain C CrystalStrcture of Dsfv Mrl In complex with peptide ,Antigen of the Mutant Epideral Growth factor receptor, Egfrviii, At liquid Nitrogei, Temperature.
Anti-EGFR-ⅤⅢ  is mainly used for the study of brain tumor EGFR- III is different from the normal epidermal growth factor receptor mutations in epidermal. Growth factor EGFRvIII abnormal cell growth signal, which leads to stop the proliferation of glioblastoma cells, proliferation.
It includes covering signal transduction, apoptosis, cell biology and other new areas. Including tumor suppressor genes / apoptosis, cell cycle proteins, transcription regulator, steroid receptors, protein kinases, growth factors and hormones, membrane receptors, signal transduction, lymphocyte signaling, cell adhesion proteins, structural proteins, phosphorylation of casein ammonia more than a dozen categories of acid antibodies and fusion proteins, antibodies are now more than 10,000
Some scholars believe that Anti-EGFR-ⅤⅢ is benifit the patient selection in clinical trials as well as targeting individual molecules choice of treatment is very important.


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