General Knowledge of Sodium Deoxycholate

Item name: Sodium deoxycholate

Molecular formula: C24H33NaO5
Molecular weight: 424.51
CAS No.: 145-41-5

Sodium deoxycholate is an ionic detergent that is especially useful for disrupting and dissociating protein interactions. Sodium deoxycholate (deoxycholic acid) is a water-soluble, bile-acid, ionic detergent commonly used in protein methods. Sodium deoxycholate is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer), but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.


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