Rapamycin is an FDA-approved immunosuppressive and cardiology drug. It
is also an inhibtor of mammalian target of rapamycin (mTOR) pathway. mTOR controls many processes involved in metabolism and response to stress. Rapamycin may benefit animals at risk of cancers
In mammals, target of rapamycin is best known to regulate translation through the ribosomal protein S6 kinases (S6Ks) and the eukaryotic translation initiation factor 4E-binding proteins. Consistent with the contribution of translation to growth, target of rapamycin regulates cell, organ, and organismal size. The identification of the tumor suppressor proteins tuberous sclerosis1 and 2 (TSC1 and 2) and Ras-homolog enriched in brain (Rheb) has biochemically linked the target of rapamycin and
phosphatidylinositol 3-kinase (PI3K) pathways, providing a mechanism for
the crosstalk that occurs between these pathways.
Target of rapamycin is emerging as a novel antitumor target, since the target
of rapamycin inhibitor rapamycin appears to be effective against tumors
resulting from aberrantly high PI3K signaling.
Read more：http://www.acid-lactic-bacteria.com/bulk-drug/Rapamycin/
is also an inhibtor of mammalian target of rapamycin (mTOR) pathway. mTOR controls many processes involved in metabolism and response to stress. Rapamycin may benefit animals at risk of cancers
In mammals, target of rapamycin is best known to regulate translation through the ribosomal protein S6 kinases (S6Ks) and the eukaryotic translation initiation factor 4E-binding proteins. Consistent with the contribution of translation to growth, target of rapamycin regulates cell, organ, and organismal size. The identification of the tumor suppressor proteins tuberous sclerosis1 and 2 (TSC1 and 2) and Ras-homolog enriched in brain (Rheb) has biochemically linked the target of rapamycin and
phosphatidylinositol 3-kinase (PI3K) pathways, providing a mechanism for
the crosstalk that occurs between these pathways.
Target of rapamycin is emerging as a novel antitumor target, since the target
of rapamycin inhibitor rapamycin appears to be effective against tumors
resulting from aberrantly high PI3K signaling.
Read more：http://www.acid-lactic-bacteria.com/bulk-drug/Rapamycin/
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