The total recommended dose showed no significant changes in coagulation, platelet aggregation time and also with fibrinogen binding unchanged. Despite the low molecular weight heparin (LMWH) for all less than 8000 Da molecular weight heparin fragment, but still depends on the effect of each molecular weight fragments. In vitro to the drug (molecular weight 4000 ~ 6000 Da) and unfractionated heparin in comparative studies have shown that, according to their molecular weight heparin with unfractionated role compared to the drug's inhibition of thrombin reduced by about 5 times. In vivo studies also showed that subcutaneous heparin, activated partial thromboplastin time (APTT) was significantly longer than the subcutaneous application of the drug. Primarily for the prevention of orthopedic and general surgical vein thrombosis and hemodialysis cardiopulmonary bypass coagulation occurs. Prevention of thrombophlebitis (deep vein thrombosis) and pulmonary embolism, the treatment has been the formation of thrombophlebitis (deep vein thrombosis)
Read more : http://www.acid-lactic-bacteria.com/bulk-drug/Enoxaparin-Sodium/
Read more : http://www.acid-lactic-bacteria.com/bulk-drug/Enoxaparin-Sodium/
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