Item name: Hexafluoroleucine
CAS: 16198-60-0
Molecular Formula: C6H7F6NO2
Molecular Weight: 239.12 g/mol
Description: The meling point of hexafluoroleucine is 220°C .Its purity is 97%.It is irritant.The specification is 1g or 5g.
Molecular Formula: C6H7F6NO2
Molecular Weight: 239.12 g/mol
Description: The meling point of hexafluoroleucine is 220°C .Its purity is 97%.It is irritant.The specification is 1g or 5g.
One aspect of the invention relates to hexafluoroleucine and congeners thereof, and methods of making the compounds. Another aspect of the nvention relates to the synthesis of protein cores comprising hexafluoroleucine and congeners thereof. Certain peptides comprising hexafluorleucine and congeners thereof have been characterized using comparative biophysical studies. In general, the fluorinated peptides show higher thermal stability and enhanced resistance to chemical denaturation. Further, mixed hydrocarbonfluorocarbon cores self-sort into homogeneous bundles, suggesting new avenues for the design and manipulation of protein-protein interfaces.
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