Teicoplanin and vancomycin for the new glycopeptide antibiotic similar to its anti-bacterial spectrum and antibacterial activity similar to vancomycin. The role of S. aureus vancomycin greater than, less adverse reactions. The product of Gram-positive bacteria such as staphylococcus, streptococcus, enterococcus, and anaerobic-positive bacteria most sensitive. Teicoplanin pharmacodynamics of a new glycopeptide antibiotics, parenteral administration, with strong bactericidal activity. Available for intravenous or intramuscular injection once a day. The drug inhibited cell wall synthesis pathway and vancomycin, as interference in the new part of the peptidoglycan synthesis process. The drug with the peptidoglycan subunit of aminoacyl-D-alanyl-D-alanine part of the combination of sky effects, this combination will be the normal bacterial cells and cross a bridge to extend the identification of acid sites hidden up. This combination of inhibition of two aspects: the formation of cell wall chain subunit of growth or extension of the new link to a bridge across the cell wall of the final steps. Therefore, the integration and solid cell wall damaged, cell growth stopped, the cells died. As a unique mechanism of action of teicoplanin, teicoplanin-resistant rare strains. So to penicillins and cephalosporins, macrolides, tetracycline and chloramphenicol, aminoglycosides, and rifampicin-resistant Gram-positive bacteria, is still sensitive to teicoplanin.
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