Monday, May 7, 2012

Specifications of Desmopressin Acetate

Item Name:   Desmopressin Acetate
Desmopressin AcetateMolecular Formula: C46H64N14O12S2
CAS No.:      16789-98-3
Specifications of Desmopressin Acetate:
Appearance :White powder
Specific Optical Rotation (c=1,1% HAc) :-72.0~-82.0°
Water Content(Karl Fischer) :≤6.0%
Acetate Content(by HPLC) :3.0~8.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.5%
Single Impurity(by HPLC) :≤0.5%
Peptide Content(by %N) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg

Desmopressin (trade names: DDAVP, Stimate, Minirin) is a synthetic replacement for vasopressin, the hormone that reduces urine production. It may be taken nasally, intravenously, or as a tablet. Doctors prescribe desmopressin most frequently for treatment of diabetes insipidus, bedwetting or nocturia.

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