Monday, May 14, 2012

A Little Explanation of Proanp1-98 ELISA Kit

proanp1-98 ELISA Kit

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Specification: 96Test

proANP is stored in membrane-bound granules in atrial cardiocytes. Upon stimulation, these granules move to the cell surface, releasing the stored proANP (1-126). The precise location and identity of this mechanism are still the subject of some debate. This prohormone is cleaved into the mature 28 amino acid peptide ANP, also known as ANP (1-28) or α-ANP, and the amino terminal fragment ANP (1-98). The 98 aminoacid N-terminus is further processed proteolytically within the circulation to form proANP (1-30), proANP (31-67) and proANP (79-98).

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