4-nitro-2-(trifluoromethyl)benzoic acid is a type of yellowish crystal. It is most commonly used as medicine intermediate. Because of its own properties, 4-nitro-2-(trifluoromethyl)benzoic acid should be stored in normal temperature.
Item name: 4-nitro-2-(trifluoromethyl)benzoic acid
CAS: 320-94-5
Molecular Formula: C8H4F 3NO4
Formula Weight: 235.12
Description:
Density: 1.596 g /cm3
Melting Point: 134-138 ºC
Boiling Point: 306.6 °C at 760 mmHg
Flash Point: 139.2 °C
Benzoic acid was discovered in the sixteenth century. The dry distillation of gum benzoin was first described by Nostradamus (1556), and subsequently by Alexius Pedemontanus (1560) and Blaise de Vigenère (1596).
Pioneer work in 1830 through a variety of experiences based on amygdalin, obtained from bitter almonds (the fruit of Prunus dulcis) oil by Pierre Robiquet and Antoine Boutron-Charlard, two French chemists, had produced benzaldehyde but they failed in working out a proper interpretation of the structure of amygdalin that would account for it, and thus missed the identification of the benzoyl radical C7H5O. This last step was achieved some few months later (1832) by Justus von Liebig and Friedrich Wöhler, who determined the composition of benzoic acid. These latter also investigated how hippuric acid is related to benzoic acid.
In 1875 Salkowski discovered the antifungal abilities of benzoic acid, which was used for a long time in the preservation of benzoate-containing cloudberry fruits.
No comments:
Post a Comment