Thursday, May 10, 2012

General Knowledge of Triptorelin Acetate

Triptorelin Acetate
Molecular Formula: C64H82N18O13
CAS No.: 57773-63-4
Properties of Triptorelin Acetate:
storage temp.  -20°C
form  powder
Safety Information of Triptorelin Acetate:
Hazard Codes  T
Risk Statements  60
Safety Statements  53-22-36/37/39-45
WGK Germany  3

Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used at the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). In the United States, it is sold by Watson as Trelstar.In Iran Triptorelin is marketed under the brand name Variopeptyl® 0.1


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