Description of Cholic Acid

 Cholic acid is a bile acid, a white crystalline substance, insoluble in water, soluble in alcohol and acetic acid, melting point 200-201 ° C. Cholate as cholates,. Cholic acid, chenodeoxycholic acid, two major, it is by the synthesis of cholesterol the liver to produce bile acids. Two bile acids, bile derivatives on behalf of about 80 per cent of bile acids.

These derivatives by coenzyme A cholyl, conjugated to either taurine or glycine, glycyl acid and taurocholic acid, respectively, cholic acid lowered cholesterol 7-alpha-hydroxylase (bile acid synthesis rate-limiting step) , cholesterol and vice versa.This is why chenodeoxy cholic acid, bile acid, can be used to treat gallstones (because of the reduction of bile acid synthesis supersaturate stone or more. Cholic acid and chenodeoxycholic acid is the most important human bile acids. Other mammals, synthesis of deoxycholic acid-based.

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