Saturday, March 31, 2012

Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats

abstract
 In a controlled, randomized double-blind study, 26 healthy adult volunteers consumed for 21 d, 400 ml of a fermented oatmeal drink with rose hips (0.7 g/100 ml) with Lactobacillus plantarum DSM 9843 (RHL; cfu with 5 × 107 ml-1), and 22 volunteers in a second group the same amount of a pure rose-hip drink (RH).

 Significant increases in the total index of faecal concentration of carboxylic acids (p <0.05 at 1 week and P <0.01 after 3 weeks after admission), acetic acid (P <0.01 after 3 weeks after admission) and propionic acid (P <0.01 stopped after 3 weeks of intake and P <0.05 8 days after ingestion) were included in the RHL group, indicating increased fermentation in the colon. In both groups, a significant increase in the concentration of fecal lactic acid (P <0.001 after 1 and 3 weeks after admission) was obtained. There were no changes seen in the concentration of faecal butyrate.

 The number of faecal bifidobacteria and lactobacilli increased significantly in both groups after 3 weeks of use. Sulphite-reducing clostridia rapidly in the group with the product Lb plantarum DSM 9843 after 1 week of taking it, and then in the pure rose-hip group after 3 weeks of use. There were no changes seen in the number of total anaerobes, gram-negative anaerobes or total aerobes during administration.

 Lb plantarum DSM 9843 was recovered in the feces of all volunteers in the RHL group. Median levels were 7.0 (5.0 to 8.8) log10 cfu g-1 after a week of taking it, and 6.7 (5.0 to 8.9) log10 cfu g-1 after 3 weeks. The tribe has not yet been heard from the faeces of five volunteers 8 d after the administration (> 4.8 log10 cfu g-1).

 During the period of ingestion, the volunteers in the RHL group, a significant increase in stool volume, a significant decrease in flatulence and slightly softer stool. Volunteers in the RH group, a slight but significant decrease in stool volume.

No comments:

Post a Comment