Tuesday, June 5, 2012

Description of Chromium Citrate

 Chromium Citrate


Item name: Chromium Citrate
Molecular Formula: C6H5CrO7
Formula Weight: 241.1g/mol
Description: Chromium citrate is produced by the reaction of citric acid with a chromium salt. It is a highly specialised product finding used in the leather and textile industries, metal treatment and pharmaceutical manufacturing.

The chromium citrate complex [CrCIT] was synthesized and its structure was determined by infrared, UV-visible and atomic absorption spectroscopy, elemental and thermodynamic analysis. Anti-diabetic activity, oxidative DNA damage capacity and acute oral toxicity of [CrCIT] were investigated and compared with that of chromium trichloride hexahydrate. [CrCIT] was synthesized in a single step reaction by chelating chromium(III) with citric acid in aqueous solution. The molecular formula of [CrCIT] was inferred as CrC(6)H(5)O(7)·4H(2)O. The anti-diabetic activity of the complex [CrCIT] was assessed in alloxan-diabetic rats by daily oral gavage for 3 weeks. The biological activity results showed that the complex at the dose of 0.25-0.75 mg Cr/kg body weight could decrease the blood glucose level and increase liver glycogen level in alloxan-diabetic rats.

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