Friday, April 27, 2012

A Simple introduction of Hesperetin


Hesperetin
Item name:Hesperetin
CAS:520-33-2
Molecular Formula:C16H14O6
Formula Weight:          302.28
Hesperetin is a bioflavonoid and, to be more specific, a flavanone. Hesperidin (a flavonone glycoside) is water-soluble due to the presence of the sugar part in its structure, so on ingestion it releases its aglycone, i.e, hesperetin.
Hesperidin is found in Citrus fruits.
Hesperetin induced cell death in a dose-dependent manner and reduced achaete-scute complex-like 1 and chromogranin A expression, with a concomitant rise in Notch1 levels. It also induced Notch1 messenger ribonucleic acid, indicating regulation at the transcriptional level.

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