Wednesday, April 25, 2012

Simple Information About Bivalirudin Trifluoroacetate


Molecular Formula:     C98H138N24O33
CAS No.:     128270-60-0
Description of Bivalirudin Trifluoroacetate:
Appearance :White powder
Water Content(Karl Fischer) :≤5.0%
Trifluoroacetate Content(by HPLC) :≤12.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N ) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
Trifluoroacetic acid (TFA) is the simplest stable perfluorinated carboxylic acid chemical compound, with the formula CF3CO2H. It is a strong carboxylic acid due to the influence of the electronegative trifluoromethyl group. TFA is almost 100,000-fold more acidic than acetic acid. TFA is widely used in organic chemistry. TFA occurs naturally in sea water, but only in small concentrations (<200 ng/L). Therefore, TFA is prepared industrially by the electrofluorination of acetyl chloride and acetic anhydride.

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1 comment:

  1. Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors. It is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. Bivalirudin Trifluoroacetate

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