Tuesday, December 13, 2011

The efficacy of Lactobacillus fermentum



Cholesterol ReductionOne of the ways in which Lactobacillus fermentum has been seen as a probiotic is by its ability to reduce cholesterol levels. Tests conducted using several strains of Lactobacillus and cholesterol broths demonstrated that lactobacillus fermentum had the largest removal of cholesterol. One of the mechanisms by which L. fermentum may remove cholesterol through in vivo is by the absorption of cholesterol, which as a result accelerates cholesterol metabolism. Another method is by the incorporation of cholesterol in the host body into its cell membrane or walls. This would also increase resistance of the bacterial cell membranes to environmental challenge. A third mechanism is by causing the body to consume more cholesterol. L. fermentum would interfere with the recycling of bile salt and facilitate its elimination, which as a result would increase the demand for bile salt made from cholesterol.
 Lactobacillus fermentum ME-3The strain Lactobacillus fermentum ME-3 has recently been discovered and identified as an antimicrobial and antioxidative probiotic. This strain of Lactobacillus fermentum was discovered from the analysis of human fecal samples in 1994. One of the important characteristics of a probiotic microbe is the tolerance to conditions in the digestive tract. Tests conducted on the ME-3 strain in different bileconcentrations found that it was able to survive without large loss in numbers. It has also been found that Lactobacillus fermentum ME-3 has a tolerance to survive drops of pH levels. It can withstand a drop in values
​​from 4.0 to 2.5 without decreasing in numbers. These characteristics of tolerance to bile concentrations and pH levels serve to classify ME-3 as a probiotic.Read more http://www.acid-lactic-bacteria.com/lactobacillus/Lactobacillus-fermentum/

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